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What Makes Amniotic Tissue Anti-Inflammatory? A Closer Look at A2M, IL-1ra, and IL-10
Discover A2M, IL-1ra, and IL-10 — the anti-inflammatory factors naturally found in AlphaFlo® cryopreserved canine amniotic tissue allograft and their roles in tissue biology.

Why AlphaFlo® Has Become a Meaningful Part of My Clinical Approach
Bree Valensin, DVM shares how AlphaFlo® canine amniotic allograft has become a valuable addition to her clinical toolkit for orthopedic, soft tissue, and proactive canine wellness cases.

Clinical Case: Bilateral Hip Dysplasia With Objective Gait Analysis Over 29 Days
Erica Dunphy, DVM, CVMMP, CVA, CCRP Columbia Veterinary Emergency Trauma and Specialist (CVETS) | Columbia, SC Case Overview I evaluated an older German Shepherd–type dog with a known history of bilateral hip dysplasia that had progressed to notable functional...

What One Veterinarian Learned from Starting with AlphaFlo®
Dr. Mark Besancon is a practicing veterinarian, consultant, and founder of DrMark.Vet, committed to enhancing canine care through education and clinical collaboration. In this blog, he shares a personal perspective on how ongoing casework and peer collaboration have...

A Veterinarian’s Journey to Adopting AlphaFlo® in Clinical Practice
Dr. Mark Besancon is a practicing veterinarian, consultant, and founder of DrMark.Vet. He is dedicated to advancing canine care through education and clinical insight. In this blog, Dr. Besancon shares his professional experience exploring canine amniotic tissue...
Cryopreserved Liquid Amnion Product vs. Powder (Lyophilized) Amnion Product
Amniotic tissue contains naturally occurring elements such as growth factors, cytokines,extracellular matrix proteins, and exosomes. These components are intrinsic to the native structure of the amniotic membrane and fluid and may be beneficial in supporting tissue...
Wounded Police Dog Recovers with AlphaFlo®
In a remarkable case that highlights the dedication of veterinary professionals, a courageous police dog injured in the line of duty received expert care and support. The K9 officer was wounded in a shooting incident and was promptly taken to Doubletree Animal...

CASE STUDY: Oral Squamous Cell Carcinoma
Case Presentation: On February 8, 2024, an 8-year-old, spayed female Doberman Pinscher presented with a mass on the right craniolateral mandible. Biopsy samples revealed a squamous cell carcinoma. At the discretion of the veterinarian, 2.0 cc of AlphaFlo® was...
CASE STUDY: Chest Wound
Case Presentation: On May 4, 2022, a two-year-old, spayed female German Shepherd Mix presented with a large wound/ laceration on the sternum. On initial presentation, the patient required tension relieving sutures, as the wound could not be completely closed. The...

CASE STUDY: Calcanean Tendon Lesion (RH)
On September 20, 2021, a 5-year-old, male English Pointer presented with soft tissue swelling with heat noted on point of right hock. The patient was 2/5 lame with some abnormal foot placement with right hind foot. Patient was treated with Low Level Laser Therapy and...
